Prenatal Diagnosis and Fetal Therapy
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".
Deadline for manuscript submissions: closed (14 July 2023) | Viewed by 2516
Special Issue Editor
Interests: fetal therapy; fetoscopy; CDH; PPROM; TTTS; amnion flush method; 29-gauge needle; amniocentesis; prenatal diagnosis; fetal; screening; fetal abnormality; aneuploidy detection; non-invasive diagnosis
Special Issue Information
Dear Colleagues,
Prenatal Diagnosis and Fetal Therapy employ a variety of techniques to determine the health and condition of an unborn fetus. Fetal therapy is a highly specialized field of medicine requiring a careful evaluation of the fetal condition in addition to a precise anatomical definition of malformations or genetic disorders. The success of fetal therapy requires knowledge of the relevant fetal pathophysiology in each case. Microinvasive fetoscopy has become increasingly safe and is now used for several purposes, including the laser coagulation of placental anastomosis in twin-to-twin-transfusion syndrome, tracheal occlusion in fetuses with congenital diaphragmatic hernia, repair of meningomyelocele and other disorders. The treatment of preterm preliminary rupture of the fetal membranes (PPROM) with oligo/anhydramnios using the method of amnion flush with amniotic flush solution was first developed in Germany 2008 and is spreading rapidly worldwide. Invasive intraumbilical supply of growth-restricted human fetuses with placental amino acids and glucose is very promising. Genetic correction in some rare diseases in human during pregnancy is no longer a future concept. The goal of the early detection of a pathologic fetal state and fetal therapy is to favorably alter long-term outcome.
In this Special Issue of Life, we invite researchers from all over the world to share advances in our understanding of genetic and molecular pathways in the pathogenesis of fetal disorders. We invite original works and review articles dealing with new techniques, signaling pathways, novel targets for alternative antibacterial therapy of PPROM, minimally invasive fetal therapy, the presentation of TRIALs in prenatal medicine, and models for predicting prognosis.
Prof. Dr. Michael Tchirikov
Guest Editor
Manuscript Submission Information
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Keywords
- prenatal diagnosis
- human genetic
- PROM
- fetal surgery
- invasive diagnosis
- soft marker
- amnion flush method
- fetal therapy
- HELLP
- fetoscopy
- CDH
- PPROM
- TTTS
- meningomyelocele
- 29-gauge needle
- amniocentesis
- prenatal diagnosis
- fetal
- screening
- fetal abnormality
- fetal DNA/RNA
- aneuploidy detection
- non-invasive diagnosis